KMID : 0614619930250040767
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Korean Journal of Gastroenterology 1993 Volume.25 No. 4 p.767 ~ p.772
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A Case of Hereditary Site-specific Colonic Cancer (Lynch Syndrome I) with metachronous
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Abstract
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Lynch syndrome I is rare hereditary disease characterized by appearance, early in life, of multiple and primary cancer in the colon and rectum. This syndrome appears to be inherited in autosomal dominant tashion with lack of antecedent polyposis.
Individual with Lynch syndrome I has a high risk of second carcinoma either synchronous or metachronous. So, it is noted that careful follow up as weil as early diagnosis and management is very important. We reported a case of metachronous Lynch
Syndrome I with review of the literatures.
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